A&E Services and the OUHSC Fire Marshal are responsible for ensuring that the design and installation of building fire exits comply with all applicable building codes and regulations.  Operations is responsible for ensuring that water-based fire suppression systems except fire extinguishers are properly installed, maintained, serviced, and marked according to the applicable National Fire Protection Association (NFPA) codes and OSHA regulations. The individual department that purchases a non-water-based fire suppression system is responsible for ensuring that the system is properly installed, maintained, serviced, and marked according to the applicable NFPA codes and OSHA regulations.

The OUHSC Fire Marshal is responsible for developing and maintaining all fire evacuation plans and the placement, proper type, and maintenance of fire extinguishers for the Oklahoma City campus.  The EHSO-Tulsa is responsible for developing and maintaining all fire evacuation plans and the placement, proper type, and maintenance of fire extinguishers for the Tulsa campus.

OUHS does not employ a specific fire brigade and does not require employees to use fire extinguishers or other fire fighting apparatus to combat fires. However, all employees are instructed annually on how to properly operate available fire extinguishers, proper and safe procedures to extinguish fires, and procedures to alert other employees and OUHSC Police/Campus Security or other appropriate emergency personnel of the fire emergency.